排序方式: 共有163条查询结果,搜索用时 15 毫秒
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Chandrakanth Are Kelly M. McMasters Armando Giuliano Charles Balch Benjamin O. Anderson Russell Berman Riccardo Audisio Tibor Kovacs Dhairyasheel Savant Rajendra Toprani Gamal Amira Ibrahim Sallam Jeong Heum Baek Moo-Jun Baek Do Joong Park Gregorio Quintero Beulo Enrique Bargallo Rocha Hector Martinez Said Muhammad Cheema Abul AliKhan Lloyd Mack Gong Chen Claudio Almeida Quadros Tarcisio Reis Heber Salvador de Castro Ribeiro Douglas Zippel Augusto Leon Ramirez 《Annals of surgical oncology》2018,25(8):2114-2116
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Fabbro E Rubert L Quaglia S Ferrara F Kiren V Ventura A Not T 《Clinica chimica acta; international journal of clinical chemistry》2008,390(1-2):134-137
BACKGROUND: Serum anti-actin IgA antibodies (AAA) were identified in patients with celiac disease (CD), and a close correlation emerged between the presence of AAA and mucosa damage, but test for AAA found in celiacs have a wide range of sensitivity and specificity values. AIM: To compare 1) the sensitivity and specificity of untreated, calcium-chelated and heated sera from 102 celiacs, 52 sick patients and 103 healthy controls in the determination of AAA, and 2) the reliability of AAA with anti-transglutaminase antibodies (anti-tTG) in diagnosing celiac disease and in predicting intestinal damage. The intestinal derived AAA was isolated by using the phage-display library technique. RESULTS: Treated sera was significantly more sensitive than untreated (p=0.0001), and showed a significant correlation between AAA and the three degrees (3a, 3b, 3c) of intestinal damage (p=0.01). Sensitivity and specificity values of anti-tTG assay were higher than the AAA assay, and anti-tTG serum-concentration was only significantly correlated with more severe (3b and 3c) intestinal damage degrees. AAA isolated by phage display showed similar results of serum AAA in immunofluorescence assay. CONCLUSIONS: Notwithstanding correlation between AAA and celiac disease, AAA assay, also after treatments, has little to offer in screening for CD compared to the well-established anti-transglutaminase assay. 相似文献
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Prognostic value of very low plasma concentrations of troponin T in patients with stable chronic heart failure 总被引:2,自引:0,他引:2
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Carlos A C Pedra Valmir F Fontes Cesar A Esteves Carlo B Pilla Sérgio L N Braga Simone R F Pedra M Virginia T Santana M Aparecida P Silva Tarcisio Almeida J Eduardo M R Sousa 《Catheterization and cardiovascular interventions》2005,64(4):495-506
More information is needed to clarify whether stenting is superior to balloon angioplasty (BA) for unoperated coarctation of the aorta (CoA). From September 1997, 21 consecutive adolescents and adults (24 +/- 11 years) with discrete CoA underwent stenting (G1). The results were compared to those achieved by BA performed in historical group of 15 patients (18 +/- 10 years; P = 0.103; G2). After the procedure, systolic gradient reduction was higher (99% +/- 2% vs. 87% +/- 17%; P = 0.015), residual gradients lower (0.4 +/- 1.4 vs. 5.9 +/- 7.9 mm Hg; P = 0.019), gain at the CoA site higher (333% +/- 172% vs. 190% +/- 104%; P = 0.007), and CoA diameter larger (16.9 +/- 2.9 vs. 12.9 +/- 3.2 mm; P < 0.001) in G1. Aortic wall abnormalities were found in eight patients in G2 (53%) and in one in G1 (7%; P < 0.001). There was no major complication. Repeat catheterization (n = 33) and/or MRI (n = 2) was performed at a median follow-up of 1.0 year for G1 and 1.5 for G2 (P = 0.005). Gradient reduction persisted in both groups, although higher late gradients were seen in G2 (median of 0 mm Hg for G1 vs. 3 for G2; P = 0.014). CoA diameter showed no late loss in G1 and a late gain in G2 with a trend to being larger in G1 (16.7 +/- 2.9 vs. 14.6 +/- 3.9 mm; P = 0.075). Two patients required late stenting due to aneurysm formation or stent fracture in G1. Aortic wall abnormalities did not progress and one patient required redilation in G2. Blood pressure was similar in both groups at follow-up (126 +/- 12/81 +/- 11 for G1 vs. 120 +/- 15/80 +/- 10 mm Hg for G2; P = 0.149 and 0.975, respectively). Although satisfactory and similar clinical outcomes were observed with both techniques, stenting was a better means to relieve the stenosis and minimize the risk of developing immediate aortic wall abnormalities. 相似文献
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Not T Tommasini A Tonini G Buratti E Pocecco M Tortul C Valussi M Crichiutti G Berti I Trevisiol C Azzoni E Neri E Torre G Martelossi S Soban M Lenhardt A Cattin L Ventura A 《Diabetologia》2001,44(2):151-155
Aims/hypothesis. We tested the hypothesis that silent coeliac disease is more frequent than expected in both patients with Type I (insulin-dependent)
diabetes mellitus and their first-degree relatives. We evaluated how the presence of other autoimmune disorders in diabetic
patients and their first-degree relatives is related to silent, unrecognized coeliac disease. Methods. Sera from 491 subjects with Type I diabetes, 824 relatives and 4000 healthy control subjects were screened for anti-endomysial
antibodies and all those subjects who tested positive for anti-endomysial antibodies underwent intestinal biopsy. Results. We found that the prevalence of coeliac disease was 5.7 % among the diabetic patients and 1.9 % among the relatives, values
significantly higher than those found among the control subjects (p < 0.0001; p < 0.001). The prevalence of autoimmune disorders in diabetic patients with coeliac disease was significantly higher than
in subjects with Type I diabetes alone (p < 0.0001). The prevalence of autoimmune disorders in the relatives with coeliac disease was significantly higher than in
those who tested negative for anti-endomysial antibodies (p = 0.01). Conclusion/interpretation. This report provides further confirmation of the high prevalence of undiagnosed coeliac disease among diabetic patients and
their relatives. This interesting new finding is the increased presence of other autoimmune diseases in these patients, as
well as in their relatives with a delayed diagnosis for coeliac disease. Patients newly diagnosed with coeliac disease showed
excellent compliance with the gluten-free diet. This should encourage policymakers to consider introducing an easy-to-use
screening programme for diabetic patients and their relatives into everyday clinical practice, in order to prevent coeliac-associated
symptoms and the onset of additional, more serious auto-immune disorders. [Diabetologia (2001) 44: 151–155]
Received: 14 July 2000 and in revised form: 6 October 2000 相似文献